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    Beast Mode Pump is an innovative, all-encompassing, non-stimulant pump pre-workout designed to maximize vasodilation, blood flow, and cell swelling to give you intense workouts every time. With 8 research-backed ingredients proven to increase nitric oxide production and intracellular hydration, Beast Mode Pump will give you blood-gorged pumps and maximum performance in the gym. Here is an ingredient breakdown of the newest collaboration between Beast Sports Nutrition and The Guerrilla Chemist.

    L-Citrulline: One of the most commonly used pump ingredients, citrulline increases vasodilation via raising plasma arginine levels. Arginine is extensively metabolized by arginase largely before it can bind with Nitric Oxide Synthase(eNOS). eNOS converts arginine into NO and increases blood flow and elevates cyclic guanosine monophosphate(cGMP). Multiple studies show that taking the same dose of citrulline vs arginine, citrulline increases plasma arginine and NO levels higher than arginine dose.  The clinical studied dose was 8g of citrulline malate, which is the equivalent of 5.6g of pure citrulline.  This formula includes 6g of pure L-citrulline. 

    Betaine: Betaine is the methyl derivative of the amino acid glycine and is found in various beets.  It has many uses, including performance enhancing benefits from many different mechanisms: increased creatine production, increased GH production, stimulation of lipolysis(breaking down fat cells).  However, it was included in this formula because of its ability to induce intracellular hyper-hydration.  Betaine is known as an osmolyte, meaning in can increase the flow of water into your cells. This can induce cell swelling, which not only increases performance and prevents dehydration, but also results in a nasty pump. In large doses, this can have a dramatic effect on performance and pumps. Studies show that a decrease in as little as 2% hydration can affect performance negatively by up to 20%.  The clinical dose of betaine is 2.5g, which is the amount included in this formula. 

    GlycerSize® (min 65% glycerol): GlycerPump® has become one of my favorite preworkout ingredients.  It is a powdered form of glycerol, an osmolyte like betaine only much more powerful.  Glycerol can hydrogen bond(attract) with water in very large quantities. Once it bonds with all these water molecules, it can drive them into your cells, blood and tissues, creating a massive cell swelling effect. This excess water can last up to 4hr before your body breaks down glycerol and you expel the excess water. One study showed that ingesting glycerol before exercise increased time to exhaustion by 28%. Glycerol is the perfect preworkout ingredient to get crazy pumps that last during your entire workout. 

    VasoDrive-AP™: VasoDrive-AP™ is a newer ingredient to hit the market and is a very unique one.  It’s a vasodilator, but it works differently from any other pump ingredient currently available.  VasoDrive-AP™ consists of 2 lactotripeptides: Valyl-prolyl-proline and Isoluecyl-prolyl-proline.  These 2 molecules act as inhibitors of the enzyme angiotensin converting enzyme(ACE), an enzyme that causes vasoconstriction, increased blood pressure and heart function.  There are 30 studies on these lactotripeptides and their effect on vasodilation, blood flow, and decreased blood pressure. One study showed that ACE can dramatically inhibit physical performance, presumably from lack of blood flow which carries oxygen and nutrients to your muscles. Data also suggests that VasoDrive-AP™ works better the longer you take it. This ingredient adds a completely different mechanism for increased blood flow and is used at the clinical of 254mg. 

    Pomegranate Seed Extract: Pomegranate seed extract is another powerful ingredient that contains tons of active bioflavonoids that can increase vasodilation and performance in the gym.  Pomegranate contains tannins like gallotannins and ellagitannins, ellagic acid and its derivatives, gallic acid, anthocyanins/anthocyanidins, proanthocyanidins, flavonoids, polyphenols, vitamins, as well as sterols, lignans, saccharides, fatty acids, organic acids, terpenes and terpenoids, among others. These compounds have been shown to decrease blood pressure, increase blood vessel diameter, inhibit angiotensin converting enzyme(like VasoDrive AP™), exhibit strong antioxidant effects that can increase NO bioavailability(via protection from superoxide anion), and most importantly increase exercise performance. Pomegranate seed has also been shown to prevent damage and dysfunction of endothelial cells, the ones responsible for vasodilation and NO production. This formula contains 800mg of pomegranate seed extract for maximum effect.

    Bitter Melon Extract: Bitter Melon extract is a common ingredient in glucose disposal supplements because of its powerful mechanism to shuttle carbs to your muscles.  But, shuttling carbs into your muscles can also create a massive pump, which is why I included it in the formula.  The bioactives in bitter melon, like charatin, polypeptide-P, and vicine can increase the release of insulin from your pancreas. Insulin, the most anabolic hormone in the body, then drives whatever carbs you have in your system into your muscles to create glycogen. It also increases regeneration of pancreatic islet cells to enhanced enzyme mediated uptake of glucose. This can have a major pump effect on your muscles, not just from the carbs but the water carbs bring with them. There are over 140 studies showing the hypoglycemic and anti-hyperglycemic effects of this herbal insulin memetic. Bitter melon also has a strong antioxidant effect. The dose of bitter melon is 500mg, with 10% bitters. The pump will be greatly intensified if carbs are consumed pre workout.

    Pine Bark Extract: Pine bark extract contains polyphenols, catechins, and phenolcarbonic acids that can cause relaxation of your endothelial cells aka vasodilation. Studies also demonstrate that pine bark extract can enhance eNOS expression and increase the release of nitric oxide, the key modulator for increasing blood to your muscles. This compliments the mechanism of citrulline for increasing NO, blood flow and massive pumps. The studied dose of pine bark extract is 180mg, and this formula contains 200mg. 

    Nattokinase: Nattokinase is an enzyme that is found in fermented soybeans and in the Japanese food Nattō. Nattokinase is an anticoagulant agent, meaning it helps prevents blood clot formation.  It does this via inhibition of plasminogen activator inhibitor 1(PAI-1). Nattokinase has yielded similar results for blood flow enhancement as aspirin, and has protective properties against oxidative damage to your endothelial cells from Fe(III). This is a unique ingredient that compliments the other ingredients for vasodilation and blood flow very well. 

    Beast Mode Pump is a comprehensive vasodilation formula designed to increase your workout performance, increase cell volumization and give you crazy pumps in the gym. The combination of these 8 superstar ingredients have been vetted to increase nitric oxide production, vasodilation, and increase intracellular water retention for massive cell swelling via several mechanisms of action. This creates a synergistic environment for driving oxygen and nutrient-rich blood to your muscles to promote anabolism and adding inches to your arms! 

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